I have a 100 pound Doberman who extremely active and also has major food allergies. These bully sticks have been the best solution for both issues. I tried so many different treats and besides real marrow bones, these are the ONLY treats he can eat without problems. They are a life savor, literally. Additionally, as you can imagine, having a 100 pound dog playing around in the house and trying kiss everyone in the face tends to be difficult to control at times. This is when i give him a bully stick. It calms him down and keeps him busy for a while. Then, of course, he beggs for more. I just want to say thank you for making these avaliable, especially in sizes appropiate for a large dog like mine. The are the best!