We bought Cranimals because our dog had Canine Papillomas. We needed her immune system to build and fight them. We bought Cranimals for an immunity boost and by the second day, the papillomas started to go away! Papillomas go away naturally within 1-5 months, with Cranimals, ours receded in 2.5 weeks! And the dog licks the bowl clean....loves the taste! -- Becky S.